Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 3/20 | 0.38 |
| ▸ | FLT4 | P35916 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26646913 | 1.00 | FYN (0.39) | FYNTP53LOXL2LMNAP2RX3 | |
| SCHEMBL26646997 | 0.87 | TLR8 (0.41) | LMNAGAAMAPK1KDM4EMEN1 | |
| SCHEMBL26646776 | 0.83 | FYN (0.50) | FYNTP53LOXL2LMNAP2RX3 | |
| SCHEMBL30068268 | 0.83 | FYN (0.50) | FYNTP53LOXL2LMNAP2RX3 | |
| SCHEMBL26647049 | 0.79 | FYN (0.39) | FYNTP53LOXL2LMNAP2RX3 | |
| SCHEMBL30068131 | 0.79 | FYN (0.39) | FYNTP53LOXL2LMNAP2RX3 | |
| SCHEMBL26647445 | 0.79 | MAPT (0.50) | FYNTP53LMNAGAAMAPK1 | |
| SCHEMBL26975281 | 0.77 | NOS3 (0.48) | LMNAGAAKDM4EMEN1NPC1 | |
| SCHEMBL30828948 | 0.76 | FYN (0.37) | FYNTP53LOXL2LMNAMAPK1 | |
| SCHEMBL26646891 | 0.76 | FYN (0.37) | FYNTP53LOXL2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794529-A | POLO-like kinase 4 inhibitors | 欧瑞克制药公司 | 2024-03-29 | — | — | CN | disclosed |