Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214101 | 0.85 | F2RL3 (0.35) | MYCWDR5BTKDHODHKDM4E | |
| SCHEMBL20214102 | 0.84 | DYRK3 (0.35) | MYCWDR5BTKKDM4EMEN1 | |
| SCHEMBL18282149 | 0.81 | ALDH1A1 (0.34) | MYCWDR5DHODHKDM4EMEN1 | |
| SCHEMBL20214050 | 0.80 | KDM4E (0.35) | MYCWDR5ALOX5PTGS2DHODH | |
| SCHEMBL20214527 | 0.79 | F2RL3 (0.33) | MYCWDR5DHODHKDM4EMEN1 | |
| SCHEMBL28347074 | 0.78 | AKR1C3 (0.36) | MYCWDR5KDM4EMEN1KMT2A | |
| SCHEMBL18282157 | 0.77 | NPC1 (0.35) | MYCWDR5DHODHKDM4EMEN1 | |
| SCHEMBL20214040 | 0.77 | MYC (0.31) | MYCWDR5F2RL3 | |
| SCHEMBL29231587 | 0.76 | PTGER1 (0.38) | MYCWDR5ALOX5PTGS2DHODH | |
| SCHEMBL18282276 | 0.75 | KDM4E (0.36) | PTGS2DHODHKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |