Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098521 | 0.88 | HDAC1 (0.55) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL3093951 | 0.85 | HDAC1 (0.48) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL3099615 | 0.82 | HDAC1 (0.49) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL3099804 | 0.75 | HDAC1 (0.62) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL8348228 | 0.75 | HDAC1 (0.71) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL8348236 | 0.74 | HDAC1 (0.74) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL13180844 | 0.72 | HDAC1 (0.74) | HDAC1HDAC2 | |
| SCHEMBL3082990 | 0.72 | HDAC1 (0.50) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL3082988 | 0.72 | HDAC1 (0.50) | HDAC1HDAC2KDM1AMAOA | |
| SCHEMBL2640602 | 0.72 | HDAC1 (0.66) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795315-B2 | N-(2-amino-phenyl)-amide derivatives | HOFFMAN-LA ROCHE INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090203681-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203681-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | MKI67, API5, BAD | HDAC1 815/4885HDAC2 973/4885KDM1A 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.