Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643682 | 0.81 | CRBN (0.53) | CRBNDDB1POLB | |
| SCHEMBL20640939 | 0.78 | PREP (0.43) | CRBNDDB1POLBPREP | |
| SCHEMBL24491305 | 0.75 | CRBN (0.82) | CRBNDDB1POLBNPC1 | |
| SCHEMBL31726832 | 0.75 | CRBN (0.46) | CRBNDDB1POLB | |
| SCHEMBL24206923 | 0.74 | CRBN (0.69) | CRBNDDB1POLBNPC1 | |
| SCHEMBL25026926 | 0.74 | CRBN (0.70) | CRBNDDB1POLB | |
| SCHEMBL8183366 | 0.74 | CRBN (0.70) | CRBNDDB1POLB | |
| SCHEMBL25026923 | 0.74 | CRBN (0.70) | CRBNDDB1POLB | |
| SCHEMBL7828080 | 0.74 | CRBN (0.70) | CRBNDDB1POLB | |
| SCHEMBL10450802 | 0.73 | CA12 (0.43) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |