SCHEMBL30832172

SCHEMBL30832172

O=C(O)c1cc2cccc3c2n1C=CN3

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 4/20 0.40
FDPS P14324 2/20 0.39
DAO P14920 1/20 0.38
CCR2 P41597 8/20 0.37
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LDHA P00338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30430299 0.70 MCL1 (0.43) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL22687067 0.68 MCL1 (0.57) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL28844727 0.67 CCR2 (0.51) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL25503879 0.65 MCL1 (0.48) MCL1FDPSDAOALDH1A1MEN1
SCHEMBL30419432 0.65 MCL1 (0.48) MCL1FDPSDAOALDH1A1MEN1
SCHEMBL6330126 0.64 MCL1 (0.46) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL30417436 0.63 MCL1 (0.42) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL25504153 0.63 MCL1 (0.45) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL30418267 0.63 MCL1 (0.45) MCL1FDPSDAOCCR2ALDH1A1
SCHEMBL25502516 0.63 MCL1 (0.56) MCL1FDPSDAOCCR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865878-A Chiral indoline-3-one derivative and preparation method thereof 郑州大学 2024-04-12 CN disclosed