Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832371 | 0.79 | GRM5 (0.40) | PTK2HRH4RETPRKCQMEN1 | |
| SCHEMBL30832314 | 0.73 | LRRK2 (0.30) | HRH4LRRK2 | |
| SCHEMBL30832276 | 0.71 | RET (0.32) | RET | |
| SCHEMBL29999565 | 0.70 | GRM5 (0.48) | PTK2HRH4MEN1KMT2ALMNA | |
| SCHEMBL31189011 | 0.68 | MEN1 (0.54) | MEN1KMT2ARAB9ALMNAHTT | |
| SCHEMBL31491230 | 0.68 | MEN1 (0.54) | MEN1KMT2ARAB9ALMNAHTT | |
| SCHEMBL30832288 | 0.67 | RET (0.36) | RETGRM5 | |
| SCHEMBL31490763 | 0.66 | MEN1 (0.31) | MEN1KMT2ARAB9ALMNAHTT | |
| SCHEMBL31491223 | 0.65 | JAK2 (0.33) | MEN1KMT2ARAB9ALMNAHTT | |
| SCHEMBL31490762 | 0.65 | JAK2 (0.33) | MEN1KMT2ARAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568974-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BeiGene Switzerland GmbH (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024032702-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE, LTD. (KY) | 2024-02-15 | — | — | WO | disclosed |