Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999565 | 0.92 | GRM5 (0.48) | GRM5PTK2HRH4HTTLMNA | |
| SCHEMBL30832233 | 0.79 | PTK2 (0.35) | GRM5PTK2HRH4HTTLMNA | |
| SCHEMBL30789308 | 0.69 | PTK2 (0.40) | PTK2HTTLMNA | |
| SCHEMBL31572160 | 0.67 | CHRNB4 (0.35) | HRH4HTTLMNASMN1; SMN2NCOA3 | |
| SCHEMBL31572161 | 0.67 | CHRNB4 (0.35) | HRH4HTTLMNASMN1; SMN2NCOA3 | |
| SCHEMBL29933984 | 0.66 | GRM5 (0.51) | GRM5CYP1A2 | |
| SCHEMBL517094 | 0.66 | GRM5 (0.51) | GRM5CYP1A2 | |
| SCHEMBL30988180 | 0.66 | MPO (0.41) | GRM5PTK2HRH4ALDH1A1RAB9A | |
| SCHEMBL9228795 | 0.65 | NOTUM (0.49) | HTTLMNASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL17827750 | 0.65 | PDGFRB (0.50) | PTK2HRH4LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568974-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BeiGene Switzerland GmbH (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024032702-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE, LTD. (KY) | 2024-02-15 | — | — | WO | disclosed |