Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30274351 | 0.80 | HTR2A (0.74) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL274149 | 0.78 | HTR7 (1.00) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL30274448 | 0.77 | HTR7 (0.62) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL30274356 | 0.74 | HTR7 (0.70) | HTR7CYP3A4CYP2D6CYP2C19DRD2 | |
| SCHEMBL998116 | 0.74 | HTR7 (0.70) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20524868 | 0.74 | HTR7 (0.61) | HTR7CYP3A4CYP2D6CYP2C19DRD2 | |
| SCHEMBL23875880 | 0.73 | HTR7 (0.78) | HTR7CYP3A4CYP2D6CYP2C19DRD2 | |
| SCHEMBL7497502 | 0.73 | HTR2A (0.76) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3709723 | 0.73 | HTR7 (0.78) | HTR7CYP3A4CYP2D6CYP2C19DRD2 | |
| SCHEMBL6786360 | 0.73 | HTR7 (0.78) | HTR7CYP3A4CYP2D6CYP2C19DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260188-B | Preparation method of tetrahydro-beta-carboline ketone compound | 浙江理工大学 | 2024-04-02 | — | — | CN | disclosed |