Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680527 | 0.87 | NOTUM (0.37) | LMNAKMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL25423720 | 0.84 | ALDH1A1 (0.47) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL8472209 | 0.83 | SMN1; SMN2 (0.54) | MGAMGAASIMGAM2MEN1 | |
| Water SCHEMBL11223291 | 0.83 | MGAM (0.42) | MGAMGAASIMGAM2LMNA | |
| Water SCHEMBL11223284 | 0.83 | MGAM (0.42) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL221624 | 0.81 | MEN1 (0.46) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL20680249 | 0.80 | POLQ (0.40) | MEN1KMT2AALDH1A1APP | |
| SCHEMBL11223288 | 0.77 | MEN1 (0.37) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL4511931 | 0.76 | MGAM (0.39) | MGAMGAASIMGAM2THRB | |
| SCHEMBL788221 | 0.75 | KMT2A (0.51) | MGAMGAASIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580829-A | Quinoline and azaquinolines as inhibitors of CD38 | 勃林格英格翰国际有限公司 | 2024-02-20 | — | — | CN | disclosed |