SCHEMBL30833299

SCHEMBL30833299

CN(C)Cc1ccc(COc2cccc3[nH]c4ccccc4c23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.47
HTR2A P28223 3/20 0.47
DNM1 Q05193 2/20 0.46
TLR4 O00206 5/20 0.42
SRD5A2 P31213 1/20 0.42
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
CTSV O60911 1/20 0.42
CTSL P07711 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
TNKS O95271 1/20 0.41
DRD2 P14416 3/20 0.41
KDM4E B2RXH2 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
MLNR O43193 1/20 0.41
NR1I2 O75469 1/20 0.41
KCNK2 O95069 1/20 0.41
ABCB11 O95342 1/20 0.41
APP P05067 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30833300 0.87 ADRB2 (0.46) ADRB2HTR2ADNM1TLR4SRD5A2
SCHEMBL29180926 0.85 ADRB2 (0.50) ADRB2HTR2ADNM1TLR4SRD5A2
SCHEMBL4893406 0.84 SRD5A2 (0.56) ADRB2HTR2ADNM1TLR4SRD5A2
SCHEMBL29180951 0.83 ADRB2 (0.48) ADRB2DNM1TLR4SRD5A2MAPT
SCHEMBL29180946 0.83 ADRB2 (0.54) ADRB2HTR2ADNM1TLR4MAPT
SCHEMBL29180915 0.82 ADRB2 (0.47) ADRB2DNM1TLR4SRD5A2CTSV
SCHEMBL29180920 0.82 ADRB2 (0.47) ADRB2DNM1TLR4SRD5A2MAPT
SCHEMBL29180941 0.82 ADRB2 (0.52) ADRB2HTR2ADNM1TLR4SRD5A2
SCHEMBL29180973 0.82 ADRB2 (0.47) ADRB2HTR2ADNM1TLR4SRD5A2
SCHEMBL29180949 0.79 MAOB (0.47) ADRB2HTR2ADNM1TLR4SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800898-A Carbazole compound and application thereof 中国药科大学 2024-04-02 CN disclosed