Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NRAS | P01111 | 5/20 | 0.41 |
| ▸ | FLT3 | P36888 | 5/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687286 | 1.00 | CYP1A2 (0.47) | CYP1A2CYP2C19TDP1HRH3IRAK4 | |
| Hydrochloric Acid SCHEMBL30457682 | 0.99 | CYP1A2 (0.46) | CYP1A2CYP2C19TDP1HRH3IRAK4 | |
| SCHEMBL31687296 | 0.87 | CYP1A2 (0.46) | CYP1A2CYP2C19TDP1HRH3IRAK4 | |
| SCHEMBL31687285 | 0.86 | FLT3 (0.45) | CYP1A2CYP2C19HRH3IRAK4MAP4K1 | |
| SCHEMBL31687271 | 0.84 | PRKCI (0.42) | HRH3IRAK4MAP4K1HRH4HRH2 | |
| SCHEMBL31687300 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP2C19TDP1HRH3MAP4K1 | |
| SCHEMBL31634664 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP2C19TDP1HRH3MAP4K1 | |
| Hydrochloric Acid SCHEMBL30996519 | 0.79 | MC4R (0.39) | HRH3IRAK4HRH4HRH2NRAS | |
| SCHEMBL31634694 | 0.78 | MC4R (0.35) | CYP1A2CYP2C19TDP1HRH3CYP3A4 | |
| SCHEMBL25435475 | 0.77 | HDAC4 (0.53) | HRH3HRH4NRASFLT3MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620955-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024104452-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 长春金赛药业有限责任公司 | 2024-05-23 | — | — | WO | disclosed |
| CN-117736206-A | Urea derivatives as MC4R antagonists, pharmaceutical compositions and pharmaceutical applications thereof | 长春金赛药业有限责任公司 | 2024-03-22 | — | — | CN | disclosed |