Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833322 | 0.78 | CYP1A2 (0.47) | MC4RHRH3CYP1A2CYP2C19TDP1 | |
| SCHEMBL31687286 | 0.78 | CYP1A2 (0.47) | MC4RHRH3CYP1A2CYP2C19TDP1 | |
| Hydrochloric Acid SCHEMBL30457682 | 0.77 | CYP1A2 (0.46) | MC4RHRH3CYP1A2CYP2C19TDP1 | |
| SCHEMBL31634704 | 0.75 | MC4R (0.34) | MC4RHCRTR1HCRTR2CYP1A2CYP2C19 | |
| SCHEMBL31687277 | 0.75 | MC4R (0.34) | MC4RHCRTR1HCRTR2CYP1A2CYP2C19 | |
| SCHEMBL30948988 | 0.71 | USP30 (0.43) | MC4RHCRTR1HCRTR2 | |
| SCHEMBL31687296 | 0.66 | CYP1A2 (0.46) | HRH3CYP1A2CYP2C19TDP1CYP3A4 | |
| SCHEMBL25278377 | 0.65 | MC4R (0.59) | MC4R | |
| SCHEMBL31687285 | 0.65 | FLT3 (0.45) | HRH3CYP1A2CYP2C19 | |
| SCHEMBL10262761 | 0.64 | BRAF (0.45) | HCRTR1HCRTR2CYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620955-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |