SCHEMBL30833366

SCHEMBL30833366

O=P(c1ccccc1)(c1ccccc1)c1c(O)ccc2c(O)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
NPSR1 Q6W5P4 3/20 0.42
MAPT P10636 3/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP1A2 P05177 3/20 0.41
ALOX15 P16050 2/20 0.41
HPGD P15428 2/20 0.41
APP P05067 1/20 0.41
THRB P10828 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
SNCA P37840 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 2/20 0.40
POLB P06746 2/20 0.40
APOBEC3A P31941 1/20 0.40
CASP6 P55212 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17589451 0.78 NPSR1 (0.55) NPSR1MAPTALOX15TSHRTDP1
SCHEMBL11991061 0.76 NPSR1 (0.53) NPSR1MAPTALOX15TSHRTDP1
SCHEMBL9721905 0.73 IDO1 (0.87) IDO1MAPTHSD17B10CYP1A2ALOX15
SCHEMBL14020807 0.71 CA2 (0.52) NPSR1MAPTALOX15TSHRTDP1
SCHEMBL31371259 0.69 NPSR1 (0.47) NPSR1MAPTALOX15TSHRTDP1
1-Naphthol SCHEMBL6245547 0.69 CYP1A2 (0.71) IDO1MAPTHSD17B10CYP1A2ALOX15
SCHEMBL810991 0.69 CYP3A4 (0.56) NPSR1MAPTHSD17B10CYP1A2ALOX15
SCHEMBL12317648 0.69 CYP3A4 (0.56) NPSR1MAPTHSD17B10CYP1A2ALOX15
SCHEMBL29539230 0.69 CYP3A4 (0.56) NPSR1MAPTHSD17B10CYP1A2ALOX15
SCHEMBL16107538 0.68 IDO1 (0.65) IDO1NPSR1MAPTHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108762-A Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof 四川东材科技集团股份有限公司 2024-05-31 CN claimed
CN-117801017-A Main chain type phosphorus-containing active ester resin containing naphthalene structure, preparation method and application 四川东材科技集团股份有限公司 2024-04-02 CN claimed
CN-118108762-A Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof 四川东材科技集团股份有限公司 2024-05-31 CN disclosed
CN-117801017-A Main chain type phosphorus-containing active ester resin containing naphthalene structure, preparation method and application 四川东材科技集团股份有限公司 2024-04-02 CN disclosed