Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 4/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833455 | 0.82 | PDE8B (0.37) | MEN1KMT2ASTSPDE8BOPRK1 | |
| SCHEMBL30833457 | 0.82 | MEN1 (0.35) | MEN1KMT2ASTSPDE8BOPRK1 | |
| SCHEMBL17942434 | 0.82 | STS (0.43) | STSALDH1A1 | |
| SCHEMBL30833482 | 0.78 | MEN1 (0.40) | MEN1KMT2APDE8BHSD17B10NR1H2 | |
| SCHEMBL30833502 | 0.76 | MEN1 (0.42) | MEN1KMT2ASTSNR1H2NR1H3 | |
| SCHEMBL30833454 | 0.74 | KMT2A (0.40) | MEN1KMT2ASTSPDE8BHSD17B10 | |
| SCHEMBL30833513 | 0.74 | PDE8B (0.38) | MEN1KMT2APDE8BOPRK1ALDH1A1 | |
| SCHEMBL17942455 | 0.73 | STS (0.42) | STS | |
| SCHEMBL17942421 | 0.73 | STS (0.42) | MEN1KMT2ASTSALDH1A1 | |
| SCHEMBL21294369 | 0.70 | HSD17B10 (0.44) | MEN1KMT2APDE8BHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |