Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | WNT3 | P56703 | 1/20 | 0.32 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833502 | 0.88 | MEN1 (0.42) | MEN1KMT2ANR1H3NR1H2WNT3 | |
| SCHEMBL30833505 | 0.82 | MEN1 (0.38) | MEN1KMT2ANR1H3NR1H2PDE8B | |
| SCHEMBL30833399 | 0.82 | MEN1 (0.38) | MEN1KMT2ANR1H3NR1H2LMNA | |
| SCHEMBL17948866 | 0.81 | DPP4 (0.43) | — | |
| SCHEMBL30833495 | 0.78 | MEN1 (0.38) | MEN1KMT2ANR1H3NR1H2PDE8B | |
| SCHEMBL30833454 | 0.77 | KMT2A (0.40) | MEN1KMT2ANR1H3NR1H2PDE8B | |
| SCHEMBL30833501 | 0.73 | PDE8B (0.38) | MEN1KMT2APDE8BLMNANPSR1 | |
| SCHEMBL17948868 | 0.73 | GPR119 (0.43) | — | |
| SCHEMBL30833381 | 0.72 | MEN1 (0.46) | MEN1KMT2ANR1H3NR1H2WNT3 | |
| SCHEMBL21294369 | 0.71 | HSD17B10 (0.44) | MEN1KMT2APDE8BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |