Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 14/20 | 0.44 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076208 | 0.81 | HMGCR (0.43) | HMGCRCTSAACHEKDM4EALDH1A1 | |
| SCHEMBL9537924 | 0.79 | HMGCR (0.42) | HMGCRCTSAACHE | |
| SCHEMBL10910720 | 0.77 | HMGCR (0.41) | HMGCRCTSAACHEKDM4EALDH1A1 | |
| SCHEMBL525985 | 0.77 | CTSA (0.48) | HMGCRCTSAACHEKDM4EALDH1A1 | |
| SCHEMBL8383303 | 0.75 | HMGCR (0.40) | HMGCRCTSAACHEPOLB | |
| SCHEMBL8385840 | 0.75 | HMGCR (0.40) | HMGCRCTSAACHEKDM4EALDH1A1 | |
| SCHEMBL5968221 | 0.75 | HMGCR (0.40) | HMGCRCTSAACHE | |
| SCHEMBL6016751 | 0.74 | HMGCR (0.39) | HMGCRCTSAACHEKDM4EPOLB | |
| SCHEMBL5053516 | 0.74 | HMGCR (0.39) | HMGCRCTSAACHE | |
| SCHEMBL2322178 | 0.74 | HMGCR (0.39) | HMGCRCTSAACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351722-B2 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2016-02-17 | — | — | EP | claimed |
| US-20140316533-A1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2014-10-23 | — | — | US | claimed |
| US-RE43793-E1 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2012-11-06 | — | — | US | claimed |
| US-20120258148-A1 | ENDOSSEOUS IMPLANT | DESCOUTS PIERRE (FR) | 2012-10-11 | — | — | US | claimed |
| US-20100234900-A1 | ENDOSSEOUS IMPLANT | DESCOUTS PIERRE | 2010-09-16 | — | — | US | claimed |
| US-7727540-B2 | surface of implant is made from titanium or titanium alloy, implant having smooth or rough surface texture, wherein surface has been treated with organic phosphonate compound or pharmaceutically acceptable salt or ester or amide thereof; for human or animal bone | UNIVERSITE DE GENEVE (CH) | 2010-06-01 | — | — | US | claimed |
| US-7090496-B2 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2006-08-15 | — | — | US | claimed |
| EP-1351722-B1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2006-07-05 | — | — | EP | claimed |
| EP-1343545-B1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2006-07-05 | — | — | EP | claimed |
| US-20040054422-A1 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2004-03-18 | — | — | US | claimed |
| US-20040049287-A1 | Surface treated with a phosphonic acid, ester, amide or salt; orthopaedic prostheses; bone replacements or reinforcements, dentistry | UNIVERSITE DE GENEVE (CH) | 2004-03-11 | — | — | US | claimed |
| EP-1351722-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-10-15 | — | — | EP | claimed |
| EP-1343545-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-09-17 | — | — | EP | claimed |
| WO-2002040075-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |
| WO-2002040074-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2002-05-23 | — | — | WO | claimed |
| US-9730795-B2 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2017-08-15 | — | — | US | disclosed |
| EP-1351722-B2 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2016-02-17 | — | — | EP | disclosed |
| EP-1343545-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002040075-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | disclosed |
| WO-2002040074-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2002-05-23 | — | — | WO | disclosed |