Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15653265 | 0.75 | KMO (0.40) | KMOMAPTCHEK1AURKADAPK3 | |
| SCHEMBL20181741 | 0.75 | ASAH1 (0.42) | KMOUSP2POLBASAH1TLR8 | |
| SCHEMBL24984421 | 0.73 | ASAH1 (0.35) | ASAH1HDAC8GCGR | |
| SCHEMBL30410846 | 0.73 | CHEK1 (0.41) | KMOMEN1POLBMAPTHTT | |
| SCHEMBL2144798 | 0.73 | CHEK1 (0.41) | KMOMEN1POLBMAPTHTT | |
| SCHEMBL22810558 | 0.71 | ASAH1 (0.44) | POLBASAH1TLR8 | |
| SCHEMBL22502397 | 0.71 | HTR2A (0.48) | KMOMEN1USP2POLBMAPT | |
| SCHEMBL7592164 | 0.70 | KMO (0.39) | KMOMAPTCHEK1AURKADAPK3 | |
| SCHEMBL24984396 | 0.70 | HDAC8 (0.41) | ASAH1HDAC8GCGR | |
| SCHEMBL30833792 | 0.70 | CHEK1 (0.43) | KMOMEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |