Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190560 | 1.00 | MAPT (0.38) | MAPTHPGDDAOLMNACYP3A4 | |
| SCHEMBL7966906 | 0.77 | MAPT (0.42) | MAPTHPGDDAOLMNACYP3A4 | |
| SCHEMBL31295238 | 0.76 | DRD2 (0.52) | CYP3A4 | |
| SCHEMBL21768219 | 0.76 | MAPT (0.46) | MAPTHPGDDAOLMNACYP3A4 | |
| SCHEMBL1336667 | 0.74 | CHRNB4 (0.45) | CHRNB4CHRNA3 | |
| SCHEMBL2295355 | 0.73 | DRD2 (0.47) | — | |
| SCHEMBL5118709 | 0.73 | DRD2 (0.47) | — | |
| SCHEMBL2295207 | 0.73 | DRD2 (0.47) | — | |
| SCHEMBL22089840 | 0.72 | DRD2 (0.41) | — | |
| SCHEMBL28467255 | 0.71 | CYP19A1 (0.43) | MAPTCYP3A4NOS1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |