Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 10/20 | 0.63 |
| ▸ | MET | P08581 | 3/20 | 0.63 |
| ▸ | INSR | P06213 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.63 |
| ▸ | CDC7 | O00311 | 1/20 | 0.63 |
| ▸ | PLK4 | O00444 | 1/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.63 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.63 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.63 |
| ▸ | JAK2 | O60674 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | PAK4 | O96013 | 1/20 | 0.63 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805794 | 0.81 | EGFR (0.59) | ALKINSRPTK2EGFRIGF1R | |
| SCHEMBL23534120 | 0.81 | EGFR (0.59) | ALKINSRPTK2EGFRIGF1R | |
| SCHEMBL2592094 | 0.81 | ALK (0.67) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL25304543 | 0.80 | PTK2 (0.66) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL29190614 | 0.80 | ALK (0.51) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL30833788 | 0.80 | ALK (0.51) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL12570609 | 0.80 | ALK (0.67) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL25299781 | 0.79 | PTK2 (0.65) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL19601638 | 0.79 | ALK (0.65) | ALKMETINSRMAPK1PTK2 | |
| SCHEMBL886537 | 0.78 | INSR (0.71) | ALKMETINSRMAPK1PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |