Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.49 |
| ▸ | CDK19 | Q9BWU1 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 5/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190613 | 1.00 | ALK (0.49) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL30833810 | 0.91 | ALK (0.49) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL29190704 | 0.91 | ALK (0.49) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL30429763 | 0.88 | CDK2 (0.47) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL30429476 | 0.85 | PTK2 (0.48) | SYKCDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL29190525 | 0.83 | ALK (0.68) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL30833626 | 0.83 | ALK (0.45) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL29190581 | 0.83 | ALK (0.45) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL30833701 | 0.83 | ALK (0.68) | ALKCDK19SYKCDC7DAPK3 | |
| SCHEMBL29190574 | 0.81 | ALK (0.47) | ALKCDK19SYKCDC7DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |