Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.47 |
| ▸ | AURKA | O14965 | 7/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658309 | 1.00 | MAPK9 (0.47) | MAPK9MAPK10AURKAAURKBGSK3B | |
| SCHEMBL28665507 | 0.85 | MAPK9 (0.46) | MAPK9MAPK10AURKAAURKBGSK3B | |
| SCHEMBL28667763 | 0.84 | PTK2 (0.59) | ALKCDK9 | |
| SCHEMBL656938 | 0.77 | AURKA (0.57) | MAPK9AURKAAURKBGSK3BJAK2 | |
| SCHEMBL30948599 | 0.76 | GLO1 (0.48) | MAPK9AURKAAURKBGSK3BJAK2 | |
| SCHEMBL29253649 | 0.76 | GLO1 (0.48) | MAPK9AURKAAURKBGSK3BJAK2 | |
| SCHEMBL28667884 | 0.76 | EGFR (0.42) | ABCG2ALKBRD4CCNA2CDK2 | |
| SCHEMBL30948609 | 0.76 | ABCG2 (0.41) | MAPK9MAPK10ABCG2ALKBRD4 | |
| SCHEMBL30948628 | 0.75 | BRD4 (0.40) | MAPK9MAPK10ABCG2ALKBRD4 | |
| SCHEMBL29594658 | 0.75 | ALK (0.58) | MAPK9MAPK10AURKBGSK3BJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |