Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 6/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.40 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190547 | 1.00 | HRH4 (0.51) | HRH4HTR3AACVR1HRH3BMPR1B | |
| SCHEMBL30833674 | 0.95 | HRH4 (0.55) | HRH4HTR3AACVR1HRH3BMPR1B | |
| SCHEMBL29190636 | 0.87 | HRH4 (0.66) | HRH4HTR3AHRH3HCAR2MET | |
| SCHEMBL30833763 | 0.87 | HRH4 (0.66) | HRH4HTR3AHRH3HCAR2MET | |
| SCHEMBL28750186 | 0.86 | HRH4 (0.51) | HRH4HTR3AACVR1HRH3BMPR1B | |
| SCHEMBL5910594 | 0.84 | HRH3 (0.46) | HRH4HTR3AHRH3HCAR2CCR4 | |
| SCHEMBL29190695 | 0.82 | HRH4 (0.70) | HRH4HTR3AHRH3HCAR2MET | |
| SCHEMBL12928147 | 0.81 | PIK3CA (0.61) | HRH4HTR3AACVR1HRH3MELK | |
| SCHEMBL29190591 | 0.81 | HRH4 (0.46) | HRH4HTR3AHRH3MET | |
| SCHEMBL10126760 | 0.78 | GRIN2D (0.46) | HRH4HTR3AACVR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |