Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.66 |
| ▸ | HTR3A | P46098 | 6/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 4/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190636 | 1.00 | HRH4 (0.66) | HRH4HTR3AMAP4K4HRH3MET | |
| SCHEMBL29190695 | 0.94 | HRH4 (0.70) | HRH4HTR3AMAP4K4HRH3MET | |
| SCHEMBL30833751 | 0.87 | HRH4 (0.51) | HRH4HTR3AMAP4K4HRH3MET | |
| SCHEMBL29190547 | 0.87 | HRH4 (0.51) | HRH4HTR3AMAP4K4HRH3MET | |
| SCHEMBL29780593 | 0.82 | HRH4 (0.66) | HRH4HTR3AHRH3METNPC1 | |
| SCHEMBL2621746 | 0.82 | HRH4 (0.66) | HRH4HTR3AHRH3METNPC1 | |
| SCHEMBL30833674 | 0.82 | HRH4 (0.55) | HRH4HTR3AMAP4K4HRH3MET | |
| SCHEMBL3079624 | 0.82 | HRH4 (0.54) | HRH4HTR3AMAP4K4MET | |
| SCHEMBL3085877 | 0.81 | HRH4 (0.57) | HRH4HTR3AMAP4K4HRH3MET | |
| SCHEMBL606857 | 0.80 | HRH4 (1.00) | HRH4HTR3AHRH3METNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |