Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269515 | 0.89 | MAPT (0.48) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12251001 | 0.88 | MAPT (0.66) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL15910574 | 0.82 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27799614 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2103993 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29855859 | 0.77 | RAB9A (0.56) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL20299497 | 0.77 | RAB9A (0.56) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12250993 | 0.77 | MAPT (0.50) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29449417 | 0.75 | MAPT (0.51) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28879616 | 0.75 | MAPT (0.51) | MAPTMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |