Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833769 | 0.86 | ALK (0.44) | CDK19ALKEGFRIGF1RNTRK1 | |
| SCHEMBL29190593 | 0.84 | ALK (0.49) | CDK19ALKEGFRSYKULK1 | |
| SCHEMBL30833673 | 0.78 | SYK (0.45) | CDK19ALKEGFRSYKJAK3 | |
| SCHEMBL30833671 | 0.75 | JAK2 (0.42) | CDK19ALKEGFRIGF1RSYK | |
| SCHEMBL29190630 | 0.75 | EGFR (0.54) | CDK19ALKEGFRIGF1RSYK | |
| SCHEMBL30833636 | 0.74 | ALK (0.42) | CDK19ALKEGFRIGF1RSYK | |
| SCHEMBL30833758 | 0.74 | SYK (0.46) | CDK19ALKIGF1RSYKJAK3 | |
| SCHEMBL30833810 | 0.72 | ALK (0.49) | CDK19ALKEGFRIGF1RSYK | |
| SCHEMBL29190704 | 0.72 | ALK (0.49) | CDK19ALKEGFRIGF1RSYK | |
| SCHEMBL29190613 | 0.71 | ALK (0.49) | CDK19ALKEGFRIGF1RSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |