Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828247 | 1.00 | GAA (0.42) | GAAMAPTTDP1EGFRKMT2A | |
| SCHEMBL15946706 | 0.86 | LRRK2 (0.52) | LRRK2LMNACCNA2CDK2CCNK | |
| SCHEMBL30833632 | 0.84 | BCL6 (0.50) | GAAMAPTEGFRKMT2AMEN1 | |
| SCHEMBL21600781 | 0.84 | KMT2A (0.52) | MAPTEGFRKMT2ALRRK2KDM4E | |
| SCHEMBL3340093 | 0.84 | BCL6 (0.50) | GAAMAPTEGFRKMT2AMEN1 | |
| SCHEMBL24260666 | 0.82 | IGF1R (0.55) | GAAMAPTEGFRKMT2AMEN1 | |
| SCHEMBL22807434 | 0.82 | EGFR (0.42) | GAAMAPTTDP1EGFRKMT2A | |
| SCHEMBL600580 | 0.82 | KMT2A (0.51) | GAAEGFRKMT2AMEN1ALDH1A1 | |
| SCHEMBL30833802 | 0.82 | IGF1R (0.55) | GAAMAPTEGFRKMT2AMEN1 | |
| SCHEMBL30833629 | 0.82 | EGFR (0.42) | GAAMAPTTDP1EGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |