Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.54 |
| ▸ | IL1B | P01584 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833888 | 0.92 | NLRP3 (0.45) | NLRP3IL1BROCK2CCNT1CDK9 | |
| SCHEMBL30834010 | 0.91 | NLRP3 (0.44) | NLRP3IL1BROCK2PIK3CDCCNT1 | |
| SCHEMBL29030496 | 0.90 | NLRP3 (0.41) | NLRP3IL1B | |
| SCHEMBL29030501 | 0.90 | NLRP3 (0.41) | NLRP3IL1B | |
| SCHEMBL25302189 | 0.87 | NLRP3 (0.55) | NLRP3IL1B | |
| SCHEMBL25263725 | 0.87 | NLRP3 (0.55) | NLRP3IL1B | |
| SCHEMBL30833904 | 0.87 | NLRP3 (0.38) | NLRP3ROCK2CCNKCDK12 | |
| SCHEMBL30834001 | 0.86 | NLRP3 (0.62) | NLRP3IL1B | |
| SCHEMBL30833882 | 0.86 | NLRP3 (0.38) | NLRP3IL1B | |
| SCHEMBL31681910 | 0.84 | NLRP3 (0.44) | NLRP3IL1BPIK3CDDRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |