Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 14/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893683 | 1.00 | IL1B (0.54) | IL1BNLRP3EHMT2KCNH2TNF | |
| SCHEMBL22671974 | 0.77 | USP30 (0.48) | USP30 | |
| SCHEMBL29566245 | 0.77 | USP30 (0.48) | USP30 | |
| SCHEMBL30488543 | 0.75 | BTK (0.39) | IL1BNLRP3EHMT2USP30 | |
| SCHEMBL29030478 | 0.75 | BTK (0.39) | IL1BNLRP3EHMT2USP30 | |
| SCHEMBL29030479 | 0.75 | BTK (0.39) | IL1BNLRP3EHMT2USP30 | |
| SCHEMBL24575704 | 0.75 | USP30 (0.47) | IL1BNLRP3USP30 | |
| SCHEMBL31367808 | 0.75 | USP30 (0.47) | IL1BEHMT2USP30 | |
| SCHEMBL30893681 | 0.75 | USP30 (0.47) | IL1BNLRP3USP30 | |
| SCHEMBL26316096 | 0.74 | PFKFB3 (0.35) | IL1BNLRP3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |