Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27201255 | 1.00 | HRH4 (0.50) | HRH4HRH3DHFRFAAHHTR1B | |
| SCHEMBL27201295 | 0.88 | HRH4 (0.42) | HRH4HRH3DHFRFAAH | |
| SCHEMBL30885313 | 0.83 | HRH4 (0.50) | HRH4HRH3HTR1BHTR2BGPR65 | |
| SCHEMBL27201355 | 0.83 | HRH4 (0.50) | HRH4HRH3HTR1BHTR2BGPR65 | |
| SCHEMBL30834227 | 0.81 | HRH3 (0.50) | HRH4HRH3 | |
| SCHEMBL30885294 | 0.81 | HRH4 (0.50) | HRH4HRH3 | |
| SCHEMBL27201360 | 0.81 | HRH4 (0.50) | HRH4HRH3 | |
| SCHEMBL27201305 | 0.81 | HRH3 (0.50) | HRH4HRH3 | |
| SCHEMBL30885213 | 0.77 | HRH3 (0.50) | HRH4HRH3 | |
| SCHEMBL27201453 | 0.77 | HRH3 (0.50) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073502-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-04 | — | — | WO | claimed |
| WO-2024073502-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-04 | — | — | WO | disclosed |