Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 14/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885313 | 1.00 | HRH4 (0.50) | HRH4HRH3PDE10AHTR1BHTR2B | |
| SCHEMBL27201255 | 0.83 | HRH4 (0.50) | HRH4HRH3HTR1BHTR2BGPR65 | |
| SCHEMBL30834080 | 0.83 | HRH4 (0.50) | HRH4HRH3HTR1BHTR2BGPR65 | |
| SCHEMBL30885213 | 0.81 | HRH3 (0.50) | HRH4HRH3 | |
| SCHEMBL27201453 | 0.81 | HRH3 (0.50) | HRH4HRH3 | |
| SCHEMBL30834195 | 0.80 | HRH4 (0.49) | HRH4HRH3PDE10A | |
| SCHEMBL27201519 | 0.80 | HRH4 (0.49) | HRH4HRH3PDE10A | |
| SCHEMBL30834227 | 0.77 | HRH3 (0.50) | HRH4HRH3 | |
| SCHEMBL30885294 | 0.77 | HRH4 (0.50) | HRH4HRH3PDE10A | |
| SCHEMBL27201305 | 0.77 | HRH3 (0.50) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | claimed |
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | GID4, MDM2, XIAP | HRH4 4074/4885HRH3 4300/4885PDE10A 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.