Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 8/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.34 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25136322 | 0.87 | LDLR (0.38) | IDO1PDPK1GSK3BDYRK1ALDLR | |
| Hydrochloric Acid SCHEMBL29182214 | 0.86 | LDLR (0.37) | IDO1PDPK1GSK3BDYRK1ALDLR | |
| SCHEMBL30182550 | 0.83 | GPR142 (0.37) | PDPK1GSK3BDYRK1AMMP2MMP13 | |
| SCHEMBL25136313 | 0.83 | GPR142 (0.37) | PDPK1GSK3BDYRK1AMMP2MMP13 | |
| SCHEMBL25136408 | 0.77 | PDPK1 (0.39) | CYP3A4IDO1PDPK1HPGDS | |
| Hydrochloric Acid SCHEMBL29182167 | 0.76 | PDPK1 (0.39) | CYP3A4IDO1PDPK1HPGDS | |
| SCHEMBL25136435 | 0.75 | PDPK1 (0.43) | PDPK1GSK3BDYRK1A | |
| SCHEMBL30182839 | 0.75 | PDPK1 (0.43) | PDPK1GSK3BDYRK1A | |
| SCHEMBL25136318 | 0.73 | PDPK1 (0.39) | CYP3A4IDO1PDPK1GSK3BDYRK1A | |
| SCHEMBL25136179 | 0.72 | GSK3B (0.45) | CYP2D6GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813296-A | CD38 modulators and methods of use thereof | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | disclosed |