Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.42 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834647 | 1.00 | USP30 (0.42) | USP30FPR2BACE1SMARCA2SMARCA4 | |
| SCHEMBL30834655 | 1.00 | USP30 (0.42) | USP30FPR2BACE1SMARCA2SMARCA4 | |
| SCHEMBL31580347 | 0.92 | USP30 (0.42) | USP30FPR2BACE1RORC | |
| SCHEMBL31580719 | 0.92 | USP30 (0.42) | USP30FPR2BACE1RORC | |
| SCHEMBL31582194 | 0.92 | USP30 (0.42) | USP30FPR2BACE1SMARCA2SMARCA4 | |
| SCHEMBL4409882 | 0.88 | FPR2 (0.43) | USP30FPR2BACE1SMARCA2SMARCA4 | |
| SCHEMBL24584057 | 0.87 | NR1H2 (0.45) | USP30SMARCA2SMARCA4PBRM1SOS1 | |
| SCHEMBL19021651 | 0.87 | NR1H2 (0.45) | USP30SMARCA2SMARCA4PBRM1SOS1 | |
| SCHEMBL19021797 | 0.87 | NR1H2 (0.45) | USP30SMARCA2SMARCA4PBRM1SOS1 | |
| SCHEMBL31458525 | 0.87 | NR1H2 (0.45) | USP30SMARCA2SMARCA4PBRM1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025102600-A1 | NOVEL HETEROCYCLIC COMPOUND | 首药控股(北京)股份有限公司 | 2025-05-22 | — | — | WO | disclosed |
| CN-117886881-A | Chimeric compound for targeted degradation of BCL-2 protein, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |