Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 11/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402374 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL27399142 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL27401236 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL31556527 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL27399143 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL30835883 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL27400191 | 1.00 | TEAD1 (0.55) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL27399366 | 0.93 | TEAD1 (0.57) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL27399148 | 0.90 | TEAD1 (0.47) | TEAD1MAOBKCNH2HRH3GPR183 | |
| SCHEMBL30836049 | 0.86 | TEAD1 (0.57) | TEAD1MAOBBTKDCUN1D1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |