Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 14/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399668 | 1.00 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27399986 | 1.00 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27399908 | 1.00 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27400101 | 0.93 | TEAD1 (0.49) | TEAD1EGFRITKBTK | |
| SCHEMBL27400112 | 0.93 | TEAD1 (0.56) | TEAD1EGFRGAATDP1TEAD3 | |
| SCHEMBL31556577 | 0.86 | TEAD1 (0.56) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27399837 | 0.86 | TEAD1 (0.56) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL30835946 | 0.86 | TEAD1 (0.56) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27399893 | 0.86 | TEAD1 (0.56) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27400097 | 0.80 | TEAD1 (0.52) | TEAD1EGFRITKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |