Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 8/20 | 0.56 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835946 | 1.00 | TEAD1 (0.56) | TEAD1DCUN1D1EGFRITKBTK | |
| SCHEMBL31556577 | 1.00 | TEAD1 (0.56) | TEAD1DCUN1D1EGFRITKBTK | |
| SCHEMBL27399837 | 1.00 | TEAD1 (0.56) | TEAD1DCUN1D1EGFRITKBTK | |
| SCHEMBL27400097 | 0.94 | TEAD1 (0.52) | TEAD1DCUN1D1EGFRITKBTK | |
| SCHEMBL27400109 | 0.93 | TEAD1 (0.53) | TEAD1DCUN1D1EGFRITKPOLB | |
| SCHEMBL30836039 | 0.93 | TEAD1 (0.53) | TEAD1DCUN1D1EGFRITKPOLB | |
| SCHEMBL27399668 | 0.86 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27399908 | 0.86 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL30835988 | 0.86 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM | |
| SCHEMBL27399986 | 0.86 | TEAD1 (0.54) | TEAD1EGFRITKBTKNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |