Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402284 | 0.93 | MAPT (0.46) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL30835859 | 0.89 | MAPT (0.51) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL30835990 | 0.88 | MAPT (0.50) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL5237507 | 0.88 | GRM5 (0.49) | GPR119JAK2JAK1GPR183RORC | |
| SCHEMBL31556485 | 0.86 | MAPT (0.48) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL5237125 | 0.85 | GRM5 (0.47) | GPR119TACR1STSGRM5HDAC1 | |
| SCHEMBL30836034 | 0.85 | MAPT (0.47) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL30836009 | 0.84 | MAPT (0.46) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL30836018 | 0.82 | MAPT (0.44) | MAPTGPR119TACR1STSJAK2 | |
| SCHEMBL19385687 | 0.80 | MAPT (0.56) | MAPTGPR119TACR1STSGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |