Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 10/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835990 | 0.93 | MAPT (0.50) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL30836034 | 0.88 | MAPT (0.47) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL27402284 | 0.87 | MAPT (0.46) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL30835859 | 0.85 | MAPT (0.51) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL30836018 | 0.85 | MAPT (0.44) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL30835992 | 0.84 | MAPT (0.50) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL31556485 | 0.82 | MAPT (0.48) | MAPTRORCTACR1GPR119GPR183 | |
| SCHEMBL30836014 | 0.81 | GPR183 (0.44) | GPR183 | |
| SCHEMBL27399900 | 0.81 | GPR183 (0.44) | GPR183 | |
| SCHEMBL27399899 | 0.81 | GPR183 (0.44) | GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |