Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 2/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 8/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.38 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.38 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.35 |
| ▸ | TXK | P42681 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399899 | 1.00 | GPR183 (0.44) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL27399900 | 1.00 | GPR183 (0.44) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL27400001 | 0.93 | TEAD1 (0.47) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL27399901 | 0.86 | BTK (0.46) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL30835915 | 0.86 | BTK (0.46) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL31556565 | 0.86 | BTK (0.46) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL31556495 | 0.86 | BTK (0.46) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL31556516 | 0.85 | GPR183 (0.44) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL30835907 | 0.85 | GPR183 (0.44) | GPR183TEAD1BTKTET3KMT2A | |
| SCHEMBL31556538 | 0.85 | GPR183 (0.44) | GPR183TEAD1BTKTET3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |