Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 18/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.51 |
| ▸ | LIPE | Q05469 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31354281 | 0.93 | PDCD1 (0.56) | PDCD1CD274 | |
| SCHEMBL31353887 | 0.93 | PDCD1 (0.56) | PDCD1CD274 | |
| SCHEMBL31108218 | 0.85 | PDCD1 (0.50) | PDCD1CD274LIPE | |
| SCHEMBL31354155 | 0.84 | PDCD1 (0.51) | PDCD1CD274LIPE | |
| SCHEMBL30836682 | 0.82 | PDCD1 (0.56) | PDCD1CD274 | |
| SCHEMBL20293685 | 0.81 | LIPE (0.43) | PDCD1CD274LIPE | |
| SCHEMBL20293732 | 0.81 | LIPE (0.43) | PDCD1CD274LIPE | |
| SCHEMBL31108277 | 0.80 | PDCD1 (0.68) | PDCD1CD274LIPE | |
| SCHEMBL30836769 | 0.79 | LIPE (0.50) | PDCD1CD274LIPE | |
| SCHEMBL30836660 | 0.78 | LIPE (0.49) | PDCD1CD274LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024069448-A1 | SUBSTITUTED 1-ARYLAMINOCARBONYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1-HETEROARYLAMINOCARBONYL-1'-HETEROARYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-04-04 | — | — | WO | disclosed |