SCHEMBL3083689

SCHEMBL3083689

CC(C)C(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.50
ANPEP P15144 4/20 0.38
CA2 P00918 2/20 0.38
ERAP1 Q9NZ08 1/20 0.38
FDPS P14324 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MMP2 P08253 2/20 0.33
METAP1 P53582 1/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20699860 0.79 LAP3 (0.43) LAP3ANPEPCA2ERAP1FDPS
SCHEMBL19211962 0.78 LAP3 (0.43) LAP3ANPEPCA2ERAP1FDPS
SCHEMBL7511459 0.78 LAP3 (0.39) LAP3ANPEPERAP1
SCHEMBL4105786 0.76 KDM4E (0.43) LAP3ANPEPCA2FDPSALDH1A1
SCHEMBL19212143 0.76 LAP3 (0.41) LAP3ANPEPCA2ERAP1FDPS
Water SCHEMBL5935337 0.72 KDM4E (0.40) LAP3ANPEPCA2FDPSALDH1A1
SCHEMBL240710 0.72
SCHEMBL1115629 0.71 LAP3 (0.50) LAP3ANPEPCA2ERAP1FDPS
SCHEMBL14790295 0.71 LAP3 (0.50) LAP3ANPEPCA2ERAP1FDPS
SCHEMBL7964335 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140316533-A1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2014-10-23 US claimed
US-RE43793-E1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2012-11-06 US claimed
US-20120258148-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE (FR) 2012-10-11 US claimed
US-20100234900-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE 2010-09-16 US claimed
US-7727540-B2 surface of implant is made from titanium or titanium alloy, implant having smooth or rough surface texture, wherein surface has been treated with organic phosphonate compound or pharmaceutically acceptable salt or ester or amide thereof; for human or animal bone UNIVERSITE DE GENEVE (CH) 2010-06-01 US claimed
US-7090496-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2006-08-15 US claimed
EP-1343545-B1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2006-07-05 EP claimed
EP-1351722-B1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2006-07-05 EP claimed
US-20040054422-A1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2004-03-18 US claimed
US-20040049287-A1 Surface treated with a phosphonic acid, ester, amide or salt; orthopaedic prostheses; bone replacements or reinforcements, dentistry UNIVERSITE DE GENEVE (CH) 2004-03-11 US claimed
EP-1351722-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-10-15 EP claimed
EP-1343545-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-09-17 EP claimed
WO-2002040075-A1 ENDOSSEOUS IMPLANT UNIVERSITÉ DE GENÈVE (CH) 2002-05-23 WO claimed
WO-2002040074-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2002-05-23 WO claimed
US-9730795-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2017-08-15 US disclosed
US-20140316533-A1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2014-10-23 US disclosed
US-8802123-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2014-08-12 US disclosed
US-5156824-A Extracting metals especially uranium, actinides and lanthanides COMPAGNIE FRANCAISE DE MOKTA (FR) 1992-10-20 US disclosed
EP-0479813-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES. HUHTAMAEKI YHTHYMAE OY (FI) 1992-04-15 EP disclosed
US-4774262-A CROSSLINKED, BINDING, ESTERIFICATION RECOVERING METALS MINEMET RECHERCHE (FR) 1988-09-27 US disclosed