SCHEMBL30837239

SCHEMBL30837239

CCOc1cc(/C=C/C(=O)c2ccc(Cl)cc2)ccc1O

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 12/20 0.75
CXCR4 P61073 1/20 0.75
MAOB P27338 1/20 0.67
TOP2A P11388 1/20 0.66
PDE4A P27815 1/20 0.64
PDE4B Q07343 1/20 0.64
PDE4C Q08493 1/20 0.64
PDE4D Q08499 1/20 0.64
MAPT P10636 3/20 0.60
LMNA P02545 3/20 0.60
ATM Q13315 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
DHODH Q02127 1/20 0.60
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25196661 1.00 CXCL12 (0.75) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL11342200 0.90 LMNA (0.69) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL11342203 0.90 LMNA (0.69) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL30383313 0.89 MAPT (0.73) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL25221493 0.89 MAPT (0.73) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL30384277 0.89 CXCL12 (0.74) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL25216640 0.89 CXCL12 (0.74) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL25219819 0.89 CXCL12 (0.74) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL30384133 0.89 CXCL12 (0.74) CXCL12CXCR4MAOBTOP2APDE4A
SCHEMBL25185001 0.88 CXCL12 (0.75) CXCL12CXCR4MAOBTOP2APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed