Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30837299 | 0.87 | LCK (0.38) | MKNK2CCNCCDK8TSHRTGFBR1 | |
| SCHEMBL8605176 | 0.72 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10730719 | 0.69 | PTGS1 (0.50) | PTGS1PTGS2ALDH1A1ALOX15KDM4E | |
| SCHEMBL20567950 | 0.68 | MKNK2 (0.44) | MKNK2ALDH1A1HSD17B10HPGDKDM4E | |
| Water SCHEMBL11355879 | 0.68 | PTGS1 (0.49) | PTGS1PTGS2ALDH1A1ALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL11360385 | 0.68 | PTGS1 (0.49) | PTGS1PTGS2ALDH1A1ALOX15KDM4E | |
| SCHEMBL8607469 | 0.67 | PTGS1 (0.44) | PTGS1PTGS2ALDH1A1ALOX15KDM4E | |
| SCHEMBL31253437 | 0.66 | MKNK2 (0.39) | MKNK2 | |
| SCHEMBL5564401 | 0.66 | KDM4E (0.56) | ALDH1A1ALOX15HSD17B10HPGDKDM4E | |
| SCHEMBL25346710 | 0.66 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067820-A1 | TRICYCLIC COMPOUNDS AS CDK INHIBITORS AND METHODS OF USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2024-04-04 | — | — | WO | disclosed |