SCHEMBL30837831

SCHEMBL30837831

CCOc1ccc2c(c1)c(=O)n(Cc1ccc(OC)c(OC)c1)c(=O)n2C1CCN(C=O)CC1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDE7A Q13946 10/20 0.83
▸ PDE7B Q9NP56 5/20 0.77
▸ PDE8A O60658 3/20 0.77
▸ KMT2A Q03164 5/20 0.43
▸ MAPT P10636 4/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ TP53 P04637 2/20 0.41
▸ USP2 O75604 1/20 0.40
▸ GLA P06280 1/20 0.40
▸ CASR P41180 1/20 0.38
▸ SIGMAR1 Q99720 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100713 1.00 PDE7A (0.83) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL7878461 0.92 PDE7A (0.82) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL100074 0.91 PDE7A (0.91) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL99998 0.91 PDE7A (0.88) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL30837972 0.91 PDE7A (1.00) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL100114 0.91 PDE7A (0.80) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL100698 0.91 PDE7A (1.00) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL100956 0.91 PDE7A (0.91) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL30837950 0.91 PDE7A (0.91) PDE7APDE7BPDE8AKMT2AMAPT
SCHEMBL100673 0.91 PDE7A (0.91) PDE7APDE7BPDE8AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572765-A1 USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE Mitodicure GmbH (DE) 2025-06-25 — — EP disclosed
WO-2024038089-A1 USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE MITODICURE GMBH (DE) 2024-02-22 — — WO disclosed
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