Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 20/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.59 |
| ▸ | PDE1A | P54750 | 11/20 | 0.59 |
| ▸ | PDE1B | Q01064 | 11/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 11/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.59 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.49 |
| ▸ | PDE5A | O76074 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299992 | 1.00 | PDE7A (0.59) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL2680530 | 0.86 | PDE7A (0.53) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL299001 | 0.83 | PDE7A (0.52) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL29408533 | 0.83 | PDE7A (0.52) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL29408489 | 0.82 | PDE7A (0.50) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL299383 | 0.82 | PDE7A (0.50) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL30007133 | 0.81 | PDE7A (0.36) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL3020050 | 0.80 | PDE7A (0.65) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL2681275 | 0.80 | PDE7A (0.61) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL8118776 | 0.79 | PDE7A (0.59) | PDE7APDE4DPDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |