Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007144 | 0.85 | PDE7A (0.34) | PDE7APARP1PARP2KMT2A | |
| SCHEMBL29832412 | 0.83 | — | — | |
| SCHEMBL30007192 | 0.83 | PDE7A (0.34) | PDE7APDE1APDE1BPDE4DPDE1C | |
| SCHEMBL30007696 | 0.82 | PDE7A (0.32) | PDE7A | |
| SCHEMBL30837840 | 0.81 | PDE7A (0.59) | PDE7APDE1APDE1BPDE4DPDE1C | |
| SCHEMBL30007112 | 0.79 | AGTR1 (0.38) | PDE7APDE1APDE1BPDE4DPDE1C | |
| SCHEMBL30007177 | 0.72 | PDE7A (0.34) | PDE7APDE1APDE1BPDE4DPDE1C | |
| SCHEMBL29831605 | 0.70 | — | — | |
| SCHEMBL30007049 | 0.69 | POLB (0.32) | PDE7APDE1APDE1BPDE4DPDE1C | |
| SCHEMBL30006547 | 0.69 | PDE1A (0.32) | PDE7APDE1APDE1BPDE4DPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115192711-A | Use of PDE7 inhibitors for the treatment of movement disorders | 奥默罗斯公司 | 2022-10-18 | — | — | CN | disclosed |