Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.64 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.64 |
| ▸ | PDE8A | O60658 | 3/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101124 | 1.00 | PDE7A (0.64) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL30837928 | 0.92 | PDE7A (0.65) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100260 | 0.92 | PDE7A (0.65) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100882 | 0.89 | PDE7A (0.69) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL30837969 | 0.89 | PDE7A (0.69) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100973 | 0.87 | PDE7A (0.59) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100335 | 0.86 | PDE7A (0.60) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100898 | 0.86 | PDE7A (0.60) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL30837896 | 0.85 | PDE7A (0.72) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100855 | 0.85 | PDE7A (0.72) | PDE7APDE7BPDE8AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |