Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.69 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.69 |
| ▸ | PDE8A | O60658 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100882 | 1.00 | PDE7A (0.69) | PDE7APDE7BPDE8ANPSR1TSHR | |
| SCHEMBL99919 | 0.90 | PDE7A (0.78) | PDE7APDE7BPDE8ANPSR1TSHR | |
| SCHEMBL100338 | 0.90 | PDE7A (0.59) | PDE7APDE7BPDE8ADRD4OPRM1 | |
| SCHEMBL100260 | 0.89 | PDE7A (0.65) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL30837928 | 0.89 | PDE7A (0.65) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL30837924 | 0.89 | PDE7A (0.64) | PDE7APDE7BPDE8ANPSR1TSHR | |
| SCHEMBL101124 | 0.89 | PDE7A (0.64) | PDE7APDE7BPDE8ANPSR1TSHR | |
| SCHEMBL100911 | 0.89 | PDE7A (0.56) | PDE7APDE7BPDE8ANPSR1TSHR | |
| SCHEMBL100971 | 0.88 | PDE7A (0.78) | PDE7APDE7BPDE8AOPRM1OPRL1 | |
| SCHEMBL100132 | 0.88 | PDE7A (0.73) | PDE7APDE7BPDE8ANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |