SCHEMBL30838295

SCHEMBL30838295

CN1CCN(Cc2cc(C(=O)Nc3cccc(C4(c5nncn5C)CC(C)(C)C4)c3)c(=O)n(CC(F)(F)F)c2)CC1=O

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 19/20 0.43
▸ CBLC Q9ULV8 2/20 0.43
▸ CBL P22681 8/20 0.35
▸ PDCD1 Q15116 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838188 0.89 CBLB (0.43) CBLBCBLCCBL
SCHEMBL30838293 0.87 CBLB (0.51) CBLBCBLCCBL
SCHEMBL30838240 0.86 CBLB (0.41) CBLBCBLCCBL
SCHEMBL30838313 0.85 CBLB (0.43) CBLBCBLCCBL
SCHEMBL30838318 0.84 CBLB (0.39) CBLBCBLCCBL
SCHEMBL30838235 0.84 CBLB (0.39) CBLBCBLCCBL
SCHEMBL30838167 0.83 CBLB (0.45) CBLBCBLCCBL
SCHEMBL30838362 0.83 CBLB (0.39) CBLBCBLCCBL
SCHEMBL30838196 0.83 CBLB (0.41) CBLBCBLCCBL
SCHEMBL30838372 0.82 CBLB (0.41) CBLBCBLCCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
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