SCHEMBL30838338

SCHEMBL30838338

CC(C)CCNCc1cc(C(=O)Nc2cc(C3(c4nncn4C)CC4(CC(C)(C)C4)C3)ccc2F)c(=O)n(CC(F)(F)F)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PDCD1 Q15116 4/20 0.31
▸ CD274 Q9NZQ7 4/20 0.31
▸ CBLB Q13191 5/20 0.31
▸ CBL P22681 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838183 0.94 CBLB (0.31) CBLBCBL
SCHEMBL30838227 0.94 PDCD1 (0.31) PDCD1CD274CBLBCBL
SCHEMBL30838127 0.93 CBLB (0.36) CBLBCBL
SCHEMBL30838277 0.92 PDCD1 (0.32) PDCD1CD274CBLBCBL
SCHEMBL30838215 0.92 PDCD1 (0.33) PDCD1CD274CBLBCBL
SCHEMBL30838201 0.91 CBLB (0.32) CBLBCBL
SCHEMBL30838309 0.90 CBLB (0.32) CBLBCBL
SCHEMBL30838314 0.89 — —
SCHEMBL30838221 0.89 CBLB (0.32) CBLBCBL
SCHEMBL30838333 0.89 CBL (0.31) PDCD1CD274CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
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