⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30838379 | 0.97 | CBL (0.31) | — | |
| SCHEMBL30838346 | 0.93 | CBLB (0.35) | — | |
| SCHEMBL30838333 | 0.91 | CBL (0.31) | — | |
| SCHEMBL30838239 | 0.91 | CBL (0.31) | — | |
| SCHEMBL30838277 | 0.91 | PDCD1 (0.32) | — | |
| SCHEMBL30838309 | 0.90 | CBLB (0.32) | — | |
| SCHEMBL30838183 | 0.90 | CBLB (0.31) | — | |
| SCHEMBL30838199 | 0.90 | CBLB (0.39) | — | |
| SCHEMBL30838205 | 0.89 | — | — | |
| SCHEMBL30838338 | 0.89 | PDCD1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573085-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | Glenmark Pharmaceuticals Limited (IN) | 2025-06-25 | — | — | EP | claimed |
| WO-2024038378-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-02-22 | — | — | WO | claimed |